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What Is Sermorelin Acetate Growth Hormone Releasing
Hormone Therapy?
THERAPY OBJECTIVE
Sermorelin Acetate for injection is used to increase the
growth hormone and IGF-1 levels in humans.
DESCRIPTION OF SERMORELIN ACETATE
Sermorelin (ser-moe-REL-in) Acetate is a "growth
hormone-releasing hormone" (GHRH). This prescription drug
compounded by U.S. pharmacies pursuant to a physician's
prescription is injected subcutaneously. It stimulates
production of increased amounts of the body's own natural
human growth hormone. It is a truncated analog of a growth
hormone releasing factor (GRF 1-44) that is naturally
produced by the brain to stimulate pituitary production
and the body's natural secretion of human growth hormone.
The increased volume of human growth hormone (rhGH)
produced by the pituitary causes an increase in the
production of Insulin-Like Growth Factor-1 (IGF-1)
resulting in the benefits of treatment provided to the
adult patient.
Sermorelin Acetate growth hormone releasing hormone (GHRH)
stimulates the patient's pituitary gland by binding to
specific receptors to increase the production and
secretion of endogenous human growth hormone (HGH).
Sermorelin has an anabolic effect on the development on
the lean muscle tissues of the human body and provides
other benefits to the patient under therapy.
Sermorelin Acetate growth hormone releasing hormone (GHRH)
stimulates the patient's pituitary gland by binding to
specific receptors and to increase the production and
secretion of endogenous growth hormone (HGH). Sermorelin
has an anabolic effect on the development on the lean
muscle tissues of the human body and provides other
benefits to the patient under therapy.
Sermorelin acetate is dispensed as a sterile, non-pyrogenic,
lyophilized powder within a vial and is intended for
medical use bysubcutaneous injection after reconstitution
with Sodium Chloride Injection, USP. The reconstituted
solution has a pH of 5.0 to 5.5. Each vial contains
Sermorelin acetate and mannitol. The pH is adjusted with
dibasic sodium phosphate and monobasic sodium phosphate
buffer.
DESCRIPTION OF SERMORELIN GROWTH
HORMONE RELEASING HORMONE THERAPY FOR ADULTS
The following are the elements of the clinical assessment
process for prescribing Sermorelin acetate growth hormone
releasing hormone for adult patients at the Natural
Wellness Center.
- Following patient enrollment in a Sermorelin Growth
Hormone Releasing Hormone Therapy program, a clinical
assessment of each adult patient candidate is initiated
to determine whether Sermorelin Growth Hormone Releasing
Hormone Therapy is indicated because the patient is
deficient in human growth hormone and is experiencing
one or more symptoms of such deficiency
- A patient seeking to naturally increase their human
growth hormone and IGF-1 production by means of
Sermorelin Acetate Growth Hormone Releasing Hormone
Therapy reports a medical complaint that appears to be
appropriate for this prescribed treatment. A medical
complaint is a symptom. Symptoms of growth hormone
deficiency include, but are not limited to, excess body
fat, chronic fatigue, osteoporosis, muscle wasting,
insufficient strength or endurance, presenting with a
need to recover more rapidly from a wound, injury or
surgical procedure, etc.
- A physician performs a clinical assessment of the
patient presenting with a medical complaint and
treatment objective.
- The initial step in the process of clinical
assessment is for the adult patient to take a blood test
to determine if the patient has a growth hormone
deficiency in comparison to the normal range for growth
hormone among adults. If the blood test report indicates
that the patient has a growth hormone deficiency, then
the patient undergoes a physical examination following
their blood test.
- If the patient's medical complaint, medical history,
physical examination result and diagnostic blood testing
reports viewed together indicate that the adult patient
is deficient in human growth hormone, the treating
physician will render that diagnosis and prescribe the
indicated Sermorelin acetate treatment.
- When the treating physician determines to prescribe
a treatment plan of Sermorelin Acetate Growth Hormone
Releasing Hormone Therapy for a patient, a written
prescription is issued. And the physician provides the
patient with written instructions as to the dosage of
subcutaneous Sermorelin once daily self-injections to be
administered during the course of therapy.
- Some studies indicate that GHRH seems to work better
when used in conjunction with L-arginine. If the release
of HGH in pulses is important, the use of Sermorelin
Acetate with L-arginine may be superior to the use of
human growth hormone injections, but this varies from
individual to individual.
- The prescription is then filled by a compounding
pharmacy that dispenses the Sermorelin Acetate, insulin
type disposable syringes and sterile water for injection
directly to the patient.
- Sermorelin acetate is provided patients as a
sterile, non-pyrogenic, lyophilized powder within a vial
intended for subcutaneous injection after reconstitution
with bacteriostatic water for injection.
Benefits of Sermorelin Acetate Growth Hormone
Releasing Hormone Adult Therapy
Sermorelin acetate therapy consists of daily injections
of Sermorelin Acetate growth hormone releasing hormone (GHRH)
to stimulate the pituitary gland's increased natural
production of the body's own endogenous human growth
hormone (HGH).
Sermorelin acetate is a biological active analog of growth
hormone releasing factor (GRF 1-44) which is a growth
hormone releasing hormone (GHRH) that is naturally
produced by the human brain to stimulate production and
secretion of human growth hormone by the pituitary gland.
Sermorelin Acetate growth hormone releasing hormone (GHRH)
stimulates the pituitary gland by binding to specific
receptors to increase the production and secretion of
endogenous growth hormone (HGH).
The increase in the body’s growth hormone produced by the
pituitary gland in response to Sermorelin Acetate growth
hormone releasing hormone therapy has an anabolic effect
on the tissues of the body and other benefits identified
below.
This therapy consists of daily injections of Sermorelin
acetate which stimulates the pituitary gland to produce
increased natural secretion of human growth hormone. The
approved medical use for this prescription drug is to
increase growth hormone levels in children who have growth
hormone deficiency. The medical use of Sermorelin Acetate
growth hormone releasing hormone for adults deficient in
human growth hormone is an unlabeled medical use of the
drug to obtain the treatment benefits described below.
Although not specifically approved for increasing growth
hormone levels in adults, prescribing Sermorelin Acetate
for adults who have growth hormone deficiency is legally
permissible and within the discretion of the treating
physician. Since Sermorelin acetate is approved as safe
for use in children to increase their production of growth
hormone, it is considered safe for use in increasing the
natural production of growth hormone in adults deficient
in growth hormone.
Benefits of increased amounts of growth hormone in the
body as a result of Sermorelin growth hormone releasing
hormone include the following:
SERMORELIN ACEATATE GHRH ADULT
THERAPY BENEFITS
- Increases the development of lean body mass
through the development of new muscle cells
- Reduces body fat through lipolysis
- Increases energy and vitality
- Increases strength
- Increases endurance
- Accelerates healing from wounds or surgery
- Strengthens the heart
- Enhances the immune system
- Increases IGF-1 production
- Improves sleep quality
- Increases calcium retention, and strengthens and
increases the mineralization of bone or bone density.
- Increases protein synthesis and stimulates the
growth of all internal organs except the brain.
- Plays a role in fuel homeostasis.
- Reduces liver uptake of glucose, an effect that
opposes that of insulin.
- Promotes liver glucogenesis.
- Contributes to the maintenance and function of
pancreatic islets.
Sermorelin Acetate growth hormone releasing hormone
therapy is considered one medical means of reversing the
effects of aging in adults deficient in growth hormone
because of the benefits resulting from the increased
stimulation and secretion of human growth hormone by the
pituitary gland.
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